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High amounts of fluoride induce apoptosis/cell death in matured ameloblast-like LS8 cells by downregulating Bcl-2

Conclusions: We inferred that high doses of fluoride may easily target the transitional/early maturation ameloblasts and cause apoptosis or cell death. Bcl-2 might be involved in this process. (Source: Archives of Oral Biology)
MedWorm: Dentistry

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Diet Soda Is as Bad for Your Teeth as a Meth Habit

“You look at it side-to-side with ‘meth mouth’ or ‘coke mouth,’ it is startling to see the intensity and extent of damage more or less the same,” said Dr. Mohamed Bassiouny, a professor of restorative dentistry at the Temple University School of Dentistry in Philadelphia.

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ADPAC issues first annual report

Washington—The American Dental Political Action Committee received $ 1,174,166 from ADA members in 2012 and contributed $ 1,644,344 to federal candidates and committees, according to ADPAC’s first annual report.

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Philip K. Dick

“Sometimes the appropriate response to reality is to go insane.”
Quotes of the Day

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Pigmentation of the oral mucosa by PCB poisoning in Yusho patients

Conclusion: These results indicated that PCB-related compounds may be responsible for the higher prevalence of oral pigmentation in Yusho victims, even though a long time has passed since the Yusho poisoning accident. (Source: Archives of Oral Biology)
MedWorm: Dentistry

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Allcare president surrenders Indiana dental license

INDIANAPOLIS Allcare Dental & Dentures President Robert Bates agreed to surrender his Indiana dental license today after abruptly closing six of his Indiana business locations in early 2011.

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House Appropriations Committee

Washington—The Indian Health Service should consult with state dental associations on a pilot project for credentialing dentists, the House Appropriations Committee recommended in a report posted online July 31.

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Endocannabinoids mediate hyposalivation induced by inflammogens in the submandibular glands and hypothalamus

Abstract: Objective: The aim of this study was to investigate the factors that could participate on salivary glands hypofunction during inflammation and the participation of endocannabinoids in hyposalivation induced by the presence of inflammogens in the submandibular gland (SMG) or in the brain.Design: Salivary secretion was assessed in the presence of inflammogens and/or the cannabinoid receptor antagonist AM251 in the SMG or in the brain of rats. At the end of the experiments, some systemic and glandular inflammatory markers were measured and histopathological analysis was performed.Results: The inhibitory effect observed 1h after lipopolysaccharide (LPS, 50?g/50?l) injection into the SMG (ig) was completely prevented by the injection of AM251 (5?g/50?l) by the same route (P (Sourc…
MedWorm: Dentistry

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Tooth sensor stops you from lying to your dentist

It’s important for dentists to know what you put in your mouth when they’re trying to fix your teeth.

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Poor dental health may lead to Alzheimer’s, study suggests

People with poor oral hygiene or gum disease may be at a greater risk of developing Alzheimer’s disease, a new study led by The University of Central Lancashire (UCLan) School of Medicine and Dentistry suggests…
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