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Study reveals target for drug development for temporomandibular joint disorder (TMJD) – a chronic jaw pain disorder

Temporomandibular joint disorder (TMJD) is the most common form of oral or facial pain, affecting over 10 million Americans. The chronic disorder can cause severe pain often associated with chewing or biting down, and lacks effective treatments…
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Snapshots of American Dentistry-July 15

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Stephen Vizinczey

“Strange as it seems, no amount of learning can cure stupidity, and higher education positively fortifies it.”
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Histologic evaluation and immunohistochemical localization of STRO-1 and BMP-4 in rat immature teeth: A comparison between vital and induced pulp necrosis

Conclusion: STRO-1-positive precursor cells were not detected in the apical papilla. BMP-4 expression has not been detected during infection. (Source: Archives of Oral Biology)

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ADA standards committee to meet in October

New Orleans—The ADA Standards Committee on Dental Informatics will meet Oct. 28-30 at the Hilton New Orleans Riverside.

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Ursula K. LeGuin

“The only thing that makes life possible is permanent, intolerable uncertainty; not knowing what comes next.”
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High amounts of fluoride induce apoptosis/cell death in matured ameloblast-like LS8 cells by downregulating Bcl-2

Conclusions: We inferred that high doses of fluoride may easily target the transitional/early maturation ameloblasts and cause apoptosis or cell death. Bcl-2 might be involved in this process. (Source: Archives of Oral Biology)
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Diet Soda Is as Bad for Your Teeth as a Meth Habit

“You look at it side-to-side with ‘meth mouth’ or ‘coke mouth,’ it is startling to see the intensity and extent of damage more or less the same,” said Dr. Mohamed Bassiouny, a professor of restorative dentistry at the Temple University School of Dentistry in Philadelphia.

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ADPAC issues first annual report

Washington—The American Dental Political Action Committee received $ 1,174,166 from ADA members in 2012 and contributed $ 1,644,344 to federal candidates and committees, according to ADPAC’s first annual report.

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Philip K. Dick

“Sometimes the appropriate response to reality is to go insane.”
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