Conclusions PRGF shows a cytoprotective role against the negative effects of ZA on primary oral cells. Clinical relevance At present, there is no definitive treatment for bisphosphonates-related osteonecrosis of the jaw (BRONJ), being mainly palliatives. Our results revealed that PRGF has a cytoprotective role in cells exposed to zoledronic acid, thus providing a reliable adjunctive therapy for the treatment of BRONJ pathology. (Source: Clinical Oral Investigations)
MedWorm: Dentistry
PRGF exerts a cytoprotective role in zoledronic acid-treated oral cells
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– July 24, 2015
