Abstract In this review, we critically evaluate the case–control studies examining the relationship between rheumatoid arthritis (RA) and periodontitis, two common chronic inflammatory diseases with a similar host-mediated pathogenesis. We review the “two-hit” periodontitis model that our group previously proposed, in which we elucidate how a systemic disease such as RA can potentially exacerbate or initiate periodontitis. Furthermore, we discuss adjunctive host modulation therapy, originally developed for periodontitis (i.e., subantimicrobial-dose doxycycline alone or in combination with an anti-inflammatory agent), to simultaneously mitigate RA and periodontitis. Finally, we review studies describing periodontal treatment effects on both RA disease activity measures and sy…
MedWorm: Dentistry
The Link Between Periodontitis and Rheumatoid Arthritis: A Periodontist’s Perspective
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– December 25, 2014
More people taking dental vacations
SIX STATES WHERE THE FLU IS CONSIDERED WIDESPREAD. IT ALSO SAYS CASES ARE ON THE RISE.
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– December 25, 2014
Host Responses in the Link Between Periodontitis and Rheumatoid Arthritis
Abstract Periodontitis and rheumatoid arthritis (RA) are common chronic inflammatory conditions and share many clinical and pathologic features. There is evidence to suggest that similar profiles of cytokine genotypes and their coding proteins are involved in the pathogenesis of periodontitis and RA. In particular, constitutive overproduction of pro-inflammatory cytokines, including tumor necrosis factor-alpha (TNF-?) and interleukin-6 (IL-6), has been implicated to play a pathologic role in the two inflammatory diseases. Results from studies with animal and human subjects have suggested an improvement of periodontal inflammatory condition after treatment with TNF-? inhibitors. Likewise, IL-6 receptor inhibition therapy has been suggested to have an effect on control of periodon…
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– December 24, 2014
Ian Taylor, CDT
The BRIDGE is an online network from LMT dedicated exclusively for members of the Dental Laboratory community. Join free to connect with Ian.
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– December 24, 2014
Sugary drinks duty will save countless teeth, charity says
A 20p per litre duty on sugary drinks would help to eradicate tooth decay and save the NHS millions of pounds in wasted resources.
Dentistry News From Medical News Today
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– December 24, 2014
Gene Fowler
“Men are not against you; they are merely for themselves.”
Quotes of the Day
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– December 23, 2014
Impact of implant support on mandibular free?end base removable partial denture: theoretical study
ConclusionsThe shear forces and bending moments subjected to mandibular free?end base RPDs were found to decrease with the addition of implant support. However, the impact of implant support varied with the location of implant in this theoretical study. (Source: Clinical Oral Implants Research)
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– December 23, 2014
Precise-Fit
The BRIDGE is an online network from LMT dedicated exclusively for members of the Dental Laboratory community. Join free to learn more about Precise-Fita and other services.
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– December 23, 2014
Tooth loss in seniors linked to mental and physical decline
A study of older adults in England found those who had none of their own teeth fared worse in memory and walking speed tests than counterparts who still had some natural teeth.
Dentistry News From Medical News Today
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– December 23, 2014
Penn Jillette
“Channeling is just bad ventriloquism. You use another voice, but people can see your lips moving.”
Quotes of the Day
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– December 22, 2014
