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Effects of human vascular endothelial growth factor on reparative dentin formation.

Authors: Zhang J, Liu X, Yu W, Zhang Y, Shi C, Ni S, Liu Q, Li X, Sun Y, Zheng C, Sun H Abstract It is a challenge for dentists to save dental pulp in patients with pulp disease without resorting to root canal therapy. Formation of tertiary dentin to maintain pulp vitality is a key odontoblast response to dental pulp injury. Vascular endothelial growth factor (VEGF) is the most potent angiogenic and vasculogenic factor involved in tertiary dentin formation. It was hypothesized that VEGF may be used to treat pulp diseases such as pulpitis. To explore this hypothesis, the first step was to assess whether VEGF affects dental pulp cells to promote reparative dentin formation. In the current study, an AdCMV?hVEGF vector was constructed to deliver hVEGF into dental pulp cells of exfoli…

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Hundreds to get free dental care in the Valley

Hundreds of people have been lined up outside the Veterans Memorial Coliseum in Phoenix since Thursday to meet with the dentist. An estimated 2,000 people will receive free dental work Friday and Saturday.

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More pain before root canal, less to gain from anesthesia

Before starting any root canal procedure, dental surgeons reach for a local anesthetic.
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Marginal bone level changes and implant stability after loading are not influenced by baseline microstructural bone characteristics: 1?year follow?up

ConclusionMicrostructural bone characteristics of implant sites have no effect on changes in marginal bone level and implant stability as measured by RFA. Bone morphology cannot predict implant treatment success over time. (Source: Clinical Oral Implants Research)
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Dental barriers: Some seniors challenged to keep teeth healthy

One-fifth of adults over 75 haven’t seen a dentist in the past five years and it can have serious health risks, but a lot of people don’t have insurance to pay for it. Thinkstock.

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In vitro assessment of a collagen/alginate composite scaffold for regenerative endodontics

ConclusionThe composite scaffold could present substantial benefits compared to synthetic materials. It could provide a favorable healing environment in the root canal conducive for regenerative endodontics and is therefore appropriate to be evaluated in vivo in further studies.This article is protected by copyright. All rights reserved. (Source: International Endodontic Journal)

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Study clarifies the oral consequences of methamphetamine abuse

A multidisciplinary group of researchers from the UCLA School of Dentistry, the UCLA Fielding School of Public Health and the UCLA Integrated Substance Abuse Program have published new findings that provide conclusive evidence of disproportionately high rates of dental disease in methamphetamine abusers. In the largest study of meth abusers to date, Dr. Vivek Shetty and his colleagues systematically investigated the patterns and severity of dental disease in 571 methamphetamine abusers.

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ADA Health Policy Institute releases comprehensive state-by-state analysis of the U.S. oral health care system

The American Dental Association Health Policy Institute (HPI) today published a first-of-its-kind comprehensive report, “The Oral Health Care System: A State-by-State Analysis.
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Philip G. Hamerton

“Have you ever observed that we pay much more attention to a wise passage when it is quoted than when we read it in the original author?”
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Use of Medical Dental Sleep Appliance in the management of severe obstructive sleep apnoea: A case series

The objective assessment was made by comparing base line AHI (apnoea–hypopnoea index) and AHI with appliance in situ which showed an improvement of 99% and 55%, respectively. The secondary objective is to provide an overview of clinical and laboratory steps in the fabrication of MDSA. (Source: Journal of Pierre Fauchard Academy (India Section))

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