Hypoxia?inducible factor?1? inhibits interleukin?6 and ?8 production in gingival epithelial cells during hypoxia

ConclusionOur results suggest that the gingival epithelium is exposed to low oxygen tension in periodontal tissue and that this hypoxic condition modulates the local inflammatory response of gingival epithelial cells in an HIF?1??dependent manner. (Source: Journal of Periodontal Research)
MedWorm: Dentistry