ConclusionsArginine-containing toothpaste can significantly reduce the lactic acid production from thein situ plaques to a low level without changing the metabolic activity, live/dead bacteria ratio and total biofilm biomass through a critical clinical randomized double-blinded crossover study.Clinical significanceArginine is a potential ecological prevention and control agent for dental caries. Meanwhile, thein situ model is an easy and pragmatic way to evaluate oral hygiene products (clinical trial registration: ChiCTR-INR-16010226). (Source: Dental Technology Blog)
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