Zinc-Replacement Therapy may not Reduce Oral Pain in Patients with Zinc-Deficient Burning Mouth Syndrome (BMS)

Article Title and Bibliographic Information: Zinc deficiency may be a cause of burning mouth syndrome as zinc replacement therapy has therapeutic effects.Cho GS, Han MW, Lee B, Roh J, Choi S, Cho K, et al.J Oral Pathol Med 2010;39(9):722-7.Reviewers: Vinodh Bhoopathi, BDS, MPH, DScD, Ana Karina Mascarenhas, BDS, MPH, DrPHPurpose/Question: In patients with BMS and low serum zinc levels, does zinc-replacement therapy reduce pain? Authors using an animal model also attempted to demonstrate a causal relationship between BMS and zinc deficiencySource of Funding: Information not availableType of Study/Design: Randomized controlled trialLevel of Evidence: Level 2: Limited-quality, patient-oriented evidenceStrength of Recommendation Grade: Not applicable (Source: The Journal of Evidence-Based Den…
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