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The effect of propidium monoazide treatment on the measured bacterial composition of clinical samples after the use of a mouthwash

Conclusion The necessity to use a PMA treatment to block the DNA from dead cells in clinical studies aimed at measuring compositional shifts after the use of a mouthwash is limited to salivary samples. Clinical relevance Measuring shifts in the oral microbiome could be hampered by the presence of DNA from dead cells. (Source: Clinical Oral Investigations)
MedWorm: Dentistry

Posted in Dental News.

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