Levels of interleukin?37 in gingival crevicular fluid, saliva, or plasma in periodontal disease

ConclusionsIL?37 was expressed in all biofluids. According to our findings, the total amount of IL?37 in gingival crevicular fluid, or salivary or plasma concentrations of IL?37, may not be useful diagnostic markers to differentiate periodontal disease and the periodontally healthy condition. The difference in gingival crevicular fluid IL?37 concentration between the study groups may be a result of the variation in gingival crevicular fluid volume, as suggested by the negative correlation between gingival crevicular fluid volume and gingival crevicular fluid IL?37 concentration. In the light of our findings, it seems that IL?37 is not involved in periodontal disease. Further comprehensive studies may clarify this issue more clearly. (Source: Journal of Periodontal Research)

MedWorm: Dentistry