Diet and the risk of head and neck cancer: a pooled analysis in the INHANCE consortium

Abstract  We investigated the association between diet and head and neck cancer (HNC) risk using data from the International Head and
Neck Cancer Epidemiology (INHANCE) consortium. The INHANCE pooled data included 22 caseâ??control studies with 14,520 cases
and 22,737 controls. Center-specific quartiles among the controls were used for food groups, and frequencies per week were
used for single food items. A dietary pattern score combining high fruit and vegetable intake and low red meat intake was
created. Odds ratios (OR) and 95% confidence intervals (CI) for the dietary items on the risk of HNC were estimated with a
two-stage random-effects logistic regression model. An inverse association was observed for higher-frequency intake of fruit
(4th vs. 1st quartile OR =&n…
MedWorm: Dentistry