Comparison of gene expression between mandibular and iliac bone-derived cells

Conclusions Site-specific differences between jaw and long bones can be explained by the differences in gene expression patterns. Our results suggest that bone cell-derived cells maintain the genetic characteristics of their embryological origin. Clinical relevance This study revealed fundamental differences in gene expression between the mandibular and iliac bone in humans. These differences could be important for understanding jaw bone-specific development of bisphosphonate-related osteonecrosis of the jaw. (Source: Clinical Oral Investigations)
MedWorm: Dentistry