{"id":933,"date":"2012-07-15T05:00:05","date_gmt":"2012-07-15T05:00:05","guid":{"rendered":"http:\/\/elkhorndenture.com\/blog\/neutrophil-superoxide-production-in-the-presence-of-cigarette-smoke-extract-nicotine-and-cotinine\/"},"modified":"2012-07-15T05:00:05","modified_gmt":"2012-07-15T05:00:05","slug":"neutrophil-superoxide-production-in-the-presence-of-cigarette-smoke-extract-nicotine-and-cotinine","status":"publish","type":"post","link":"http:\/\/elkhorndenture.com\/blog\/neutrophil-superoxide-production-in-the-presence-of-cigarette-smoke-extract-nicotine-and-cotinine\/","title":{"rendered":"Neutrophil superoxide production in the presence of cigarette smoke extract, nicotine and cotinine."},"content":{"rendered":"<p>CONCLUSIONS: Stable water-soluble components of cigarette smoke directly induce superoxide generation by otherwise unstimulated neutrophils, but reduce superoxide responses of cells to pathologically relevant stimuli. These data suggest potential neutrophil-mediated mechanisms by which smoking may initiate and maintain oxidative stress at periodontally healthy sites and participate in disease progression, by reducing innate immune responses.<br \/>\n    PMID: 22607095 [PubMed &#8211; in process] (Source: Journal of Clinical Periodontology)<br \/>\n<a rel=\"nofollow\" href=\"http:\/\/www.medworm.com\/index.php?rid=6171853&#038;cid=d_11_11_f&#038;fid=28257&#038;url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2FPubMed%2F22607095%3Fdopt%3DAbstract\">MedWorm: Dentistry<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>CONCLUSIONS: Stable water-soluble components of cigarette smoke directly induce superoxide generation by otherwise unstimulated neutrophils, but reduce superoxide responses of cells to pathologically relevant stimuli. These data suggest potential neutrophil-mediated mechanisms by which smoking may initiate and maintain oxidative stress at periodontally healthy sites and participate in disease progression, by reducing innate immune responses. PMID: [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[5],"tags":[2583,2587,2585,2579,2586,2582,2581,2584,2580],"class_list":["post-933","post","type-post","status-publish","format-standard","hentry","category-dental-news","tag-cigarette","tag-cotinine","tag-extract","tag-neutrophil","tag-nicotine","tag-presence","tag-production","tag-smoke","tag-superoxide"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p1YapV-f3","_links":{"self":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts\/933","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/comments?post=933"}],"version-history":[{"count":0,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts\/933\/revisions"}],"wp:attachment":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/media?parent=933"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/categories?post=933"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/tags?post=933"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}