{"id":7522,"date":"2016-10-30T04:00:49","date_gmt":"2016-10-30T04:00:49","guid":{"rendered":"http:\/\/elkhorndenture.com\/blog\/dentistry-new-biotechnology-to-inhibit-microrna-activity-and-novel-applications\/"},"modified":"2016-10-30T04:00:49","modified_gmt":"2016-10-30T04:00:49","slug":"dentistry-new-biotechnology-to-inhibit-microrna-activity-and-novel-applications","status":"publish","type":"post","link":"http:\/\/elkhorndenture.com\/blog\/dentistry-new-biotechnology-to-inhibit-microrna-activity-and-novel-applications\/","title":{"rendered":"Dentistry: New biotechnology to inhibit microRNA activity and novel applications"},"content":{"rendered":"<p>In this study, researchers generated a novel RNA-based hairpin molecule carrying an anti-sense miR seed sequence that effectively knocks down endogenous miRs and mitigates their effects on messenger RNA in the cell. By using a native RNA-based molecule for miR knockdown, the PMIS platform avoids many of the traditional pitfalls associated with miR inhibition using synthetic oligonucleotides. (Source: ScienceDaily Headlines)<\/p>\n<div id=\"medworm\">\n<p><b><i>MedWorm Sponsor Message:<\/i><\/b> Directory of the best <a href=\"http:\/\/www.thejanuarysales.com\/\">January Sales<\/a> in the UK. Find the best <a href=\"http:\/\/www.thejanuarysales.com\/\">Christmas presents<\/a> too.<\/p>\n<\/div>\n<p><a rel=\"nofollow\" href=\"http:\/\/medworm.com\/index.php?rid=170795350&#038;cid=d_11_58_f&#038;fid=23305&#038;url=https%3A%2F%2Fwww.sciencedaily.com%2Freleases%2F2016%2F03%2F160318085635.htm\">MedWorm: Dentistry<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In this study, researchers generated a novel RNA-based hairpin molecule carrying an anti-sense miR seed sequence that effectively knocks down endogenous miRs and mitigates their effects on messenger RNA in the cell. By using a native RNA-based molecule for miR knockdown, the PMIS platform avoids many of the traditional pitfalls associated with miR inhibition using [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[5],"tags":[4167,1896,9535,58,6388,9536,2015],"class_list":["post-7522","post","type-post","status-publish","format-standard","hentry","category-dental-news","tag-activity","tag-applications","tag-biotechnology","tag-dentistry","tag-inhibit","tag-microrna","tag-novel"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p1YapV-1Xk","_links":{"self":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts\/7522","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/comments?post=7522"}],"version-history":[{"count":0,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts\/7522\/revisions"}],"wp:attachment":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/media?parent=7522"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/categories?post=7522"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/tags?post=7522"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}