{"id":6255,"date":"2015-11-15T05:00:05","date_gmt":"2015-11-15T05:00:05","guid":{"rendered":"http:\/\/elkhorndenture.com\/blog\/efficacy-and-safety-of-pilocarpine-for-radiation-induced-xerostomia-in-patients-with-head-and-neck-cancer-a-systematic-review-and-meta-analysis\/"},"modified":"2015-11-15T05:00:05","modified_gmt":"2015-11-15T05:00:05","slug":"efficacy-and-safety-of-pilocarpine-for-radiation-induced-xerostomia-in-patients-with-head-and-neck-cancer-a-systematic-review-and-meta-analysis","status":"publish","type":"post","link":"http:\/\/elkhorndenture.com\/blog\/efficacy-and-safety-of-pilocarpine-for-radiation-induced-xerostomia-in-patients-with-head-and-neck-cancer-a-systematic-review-and-meta-analysis\/","title":{"rendered":"Efficacy and safety of pilocarpine for radiation-induced xerostomia in patients with head and neck cancer: A systematic review and meta-analysis."},"content":{"rendered":"<p>CONCLUSIONS AND PRACTICAL IMPLICATIONS: On the basis of the best available evidence, the results of this meta-analysis provide evidence that pilocarpine offers statistically significant clinical benefits for the symptomatic treatment of radiation-induced xerostomia in patients with head and neck cancer. However, the authors of this systematic review found the best available evidence in the meta-analysis in 3 studies, 1 of which showed no effect. The authors of this systematic review suggest that these patients take 5 milligrams of pilocarpine 3 times daily, and that there is need for further study.     PMID: 26563850 [PubMed &#8211; as supplied by publisher] (Source: Journal of the American Dental Association)<\/p>\n<div id=\"medworm\">\n<p><b><i>MedWorm Sponsor Message:<\/i><\/b> Directory of the best <a href=\"http:\/\/www.thejanuarysales.com\/\">January Sales<\/a> in the UK. Find the best <a href=\"http:\/\/www.thejanuarysales.com\/\">Christmas presents<\/a> too.<\/p>\n<\/div>\n<p><a rel=\"nofollow\" href=\"http:\/\/www.medworm.com\/index.php?rid=150075094&#038;cid=d_11_11_f&#038;fid=41031&#038;url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F26563850%3Fdopt%3DAbstract\">MedWorm: Dentistry<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>CONCLUSIONS AND PRACTICAL IMPLICATIONS: On the basis of the best available evidence, the results of this meta-analysis provide evidence that pilocarpine offers statistically significant clinical benefits for the symptomatic treatment of radiation-induced xerostomia in patients with head and neck cancer. However, the authors of this systematic review found the best available evidence in the meta-analysis [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[5],"tags":[194,2881,204,1874,205,62,5918,8591,145,727,750,5919],"class_list":["post-6255","post","type-post","status-publish","format-standard","hentry","category-dental-news","tag-cancer","tag-efficacy","tag-head","tag-metaanalysis","tag-neck","tag-patients","tag-pilocarpine","tag-radiationinduced","tag-review","tag-safety","tag-systematic","tag-xerostomia"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p1YapV-1CT","_links":{"self":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts\/6255","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/comments?post=6255"}],"version-history":[{"count":0,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts\/6255\/revisions"}],"wp:attachment":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/media?parent=6255"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/categories?post=6255"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/tags?post=6255"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}