{"id":6251,"date":"2015-11-13T05:00:06","date_gmt":"2015-11-13T05:00:06","guid":{"rendered":"http:\/\/elkhorndenture.com\/blog\/anti%e2%80%90inflammatory-and-anti%e2%80%90osteoclastogenic-effects-of-zinc-finger-protein-a20-overexpression-in-human-periodontal-ligament-cells\/"},"modified":"2015-11-13T05:00:06","modified_gmt":"2015-11-13T05:00:06","slug":"anti%e2%80%90inflammatory-and-anti%e2%80%90osteoclastogenic-effects-of-zinc-finger-protein-a20-overexpression-in-human-periodontal-ligament-cells","status":"publish","type":"post","link":"http:\/\/elkhorndenture.com\/blog\/anti%e2%80%90inflammatory-and-anti%e2%80%90osteoclastogenic-effects-of-zinc-finger-protein-a20-overexpression-in-human-periodontal-ligament-cells\/","title":{"rendered":"Anti?inflammatory and anti?osteoclastogenic effects of zinc finger protein A20 overexpression in human periodontal ligament cells"},"content":{"rendered":"<p>ConclusionsThis study is the first to demonstrate that A20 overexpression has anti?inflammatory effects and blocks osteoclastic differentiation in a nicotine? and LPS?stimulated hPDLC model. Thus, A20 overexpression may be a potential therapeutic target in inflammatory bone loss diseases, such as periodontal disease. (Source: Journal of Periodontal Research)<br \/>\n<a rel=\"nofollow\" href=\"http:\/\/www.medworm.com\/index.php?rid=148727611&#038;cid=d_11_11_f&#038;fid=28245&#038;url=http%3A%2F%2Fonlinelibrary.wiley.com%2Fresolve%2Fdoi%3FDOI%3D10.1111%252Fjre.12332\">MedWorm: Dentistry<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>ConclusionsThis study is the first to demonstrate that A20 overexpression has anti?inflammatory effects and blocks osteoclastic differentiation in a nicotine? and LPS?stimulated hPDLC model. Thus, A20 overexpression may be a potential therapeutic target in inflammatory bone loss diseases, such as periodontal disease. (Source: Journal of Periodontal Research) MedWorm: Dentistry<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[5],"tags":[8579,8580,77,573,3911,523,537,8581,106,1856,2880],"class_list":["post-6251","post","type-post","status-publish","format-standard","hentry","category-dental-news","tag-antiinflammatory","tag-antiosteoclastogenic","tag-cells","tag-effects","tag-finger","tag-human","tag-ligament","tag-overexpression","tag-periodontal","tag-protein","tag-zinc"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p1YapV-1CP","_links":{"self":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts\/6251","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/comments?post=6251"}],"version-history":[{"count":0,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts\/6251\/revisions"}],"wp:attachment":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/media?parent=6251"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/categories?post=6251"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/tags?post=6251"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}