{"id":5826,"date":"2015-07-24T04:00:03","date_gmt":"2015-07-24T04:00:03","guid":{"rendered":"http:\/\/elkhorndenture.com\/blog\/prgf-exerts-a-cytoprotective-role-in-zoledronic-acid-treated-oral-cells\/"},"modified":"2015-07-24T04:00:03","modified_gmt":"2015-07-24T04:00:03","slug":"prgf-exerts-a-cytoprotective-role-in-zoledronic-acid-treated-oral-cells","status":"publish","type":"post","link":"http:\/\/elkhorndenture.com\/blog\/prgf-exerts-a-cytoprotective-role-in-zoledronic-acid-treated-oral-cells\/","title":{"rendered":"PRGF exerts a cytoprotective role in zoledronic acid-treated oral cells"},"content":{"rendered":"<p>Conclusions           PRGF shows a cytoprotective role against the negative effects of ZA on primary oral cells.                               Clinical relevance           At present, there is no definitive treatment for bisphosphonates-related osteonecrosis of the jaw (BRONJ), being mainly palliatives. Our results revealed that PRGF has a cytoprotective role in cells exposed to zoledronic acid, thus providing a reliable adjunctive therapy for the treatment of BRONJ pathology. (Source: Clinical Oral Investigations)<br \/>\n<a rel=\"nofollow\" href=\"http:\/\/www.medworm.com\/index.php?rid=124014770&#038;cid=d_11_11_f&#038;fid=33454&#038;url=http%3A%2F%2Flink.springer.com%2F10.1007%2Fs00784-015-1528-y\">MedWorm: Dentistry<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Conclusions PRGF shows a cytoprotective role against the negative effects of ZA on primary oral cells. Clinical relevance At present, there is no definitive treatment for bisphosphonates-related osteonecrosis of the jaw (BRONJ), being mainly palliatives. Our results revealed that PRGF has a cytoprotective role in cells exposed to zoledronic acid, thus providing a reliable adjunctive [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[5],"tags":[8215,77,8213,8212,7,1801,2556,8214],"class_list":["post-5826","post","type-post","status-publish","format-standard","hentry","category-dental-news","tag-acidtreated","tag-cells","tag-cytoprotective","tag-exerts","tag-oral","tag-prgf","tag-role","tag-zoledronic"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p1YapV-1vY","_links":{"self":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts\/5826","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/comments?post=5826"}],"version-history":[{"count":0,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts\/5826\/revisions"}],"wp:attachment":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/media?parent=5826"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/categories?post=5826"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/tags?post=5826"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}