{"id":57,"date":"2011-11-03T05:04:19","date_gmt":"2011-11-03T12:04:19","guid":{"rendered":"http:\/\/elkhorndenture.com\/blog\/the-effect-of-emdogaina%c2%ae-and-platelet-derived-growth-factor-on-the-osteoinductive-potential-of-hydroxyapatite-tricalcium-phosphate\/"},"modified":"2011-11-03T05:04:19","modified_gmt":"2011-11-03T12:04:19","slug":"the-effect-of-emdogaina%c2%ae-and-platelet-derived-growth-factor-on-the-osteoinductive-potential-of-hydroxyapatite-tricalcium-phosphate","status":"publish","type":"post","link":"http:\/\/elkhorndenture.com\/blog\/the-effect-of-emdogaina%c2%ae-and-platelet-derived-growth-factor-on-the-osteoinductive-potential-of-hydroxyapatite-tricalcium-phosphate\/","title":{"rendered":"The effect of Emdogain\u00c2\u00ae and platelet-derived growth factor on the osteoinductive potential of hydroxyapatite tricalcium phosphate"},"content":{"rendered":"<p>Abstract&nbsp;&nbsp;The aim of this study was to determine whether hydroxyapatite \u00ce\u00b2-tricalcium phosphate (HA-TCP) either alone or coated with<br \/>\n Emdogain\u00c2\u00ae (EMD) or recombinant human platelet-derived growth factor-BB (rhPDGF-BB) becomes osteoinductive in the murine thigh<br \/>\n muscle model for osteoinduction. Twenty CD1 adult male mice had gelatin capsules implanted into the thigh muscle of both hind<br \/>\n limbs. The capsules were either empty or contained one of the following: uncoated particulate HA-TCP, EMD-coated HA-TCP or<br \/>\n rhPDGF-BB-coated HA-TCP. The implant sites were assessed histologically at 4 and 8&nbsp;weeks. A semi-quantitative histological<br \/>\n examination was performed to assess the inflammatory changes, reparative processes and osteoinduction within the graft site.<br \/>\n At both 4 and 8&nbsp;w&#8230;<br \/>\n<a rel=\"nofollow\" href=\"http:\/\/www.medworm.com\/index.php?rid=5360456&#038;cid=d_11_11_f&#038;fid=33454&#038;url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj1022330n4575t75%2F\">MedWorm: Dentistry<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Abstract&nbsp;&nbsp;The aim of this study was to determine whether hydroxyapatite \u00ce\u00b2-tricalcium phosphate (HA-TCP) either alone or coated with Emdogain\u00c2\u00ae (EMD) or recombinant human platelet-derived growth factor-BB (rhPDGF-BB) becomes osteoinductive in the murine thigh muscle model for osteoinduction. Twenty CD1 adult male mice had gelatin capsules implanted into the thigh muscle of both hind limbs. The [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[5],"tags":[222,223,226,225,229,227,231,224,228,230],"class_list":["post-57","post","type-post","status-publish","format-standard","hentry","category-dental-news","tag-effect","tag-emdogaina","tag-factor","tag-growth","tag-hydroxyapatite","tag-osteoinductive","tag-phosphate","tag-plateletderived","tag-potential","tag-tricalcium"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p1YapV-V","_links":{"self":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts\/57","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/comments?post=57"}],"version-history":[{"count":0,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts\/57\/revisions"}],"wp:attachment":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/media?parent=57"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/categories?post=57"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/tags?post=57"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}