{"id":5662,"date":"2015-06-07T04:00:05","date_gmt":"2015-06-07T04:00:05","guid":{"rendered":"http:\/\/elkhorndenture.com\/blog\/a-brief-summary-of-the-articles-appearing-in-this-issue-of\/"},"modified":"2015-06-07T04:00:05","modified_gmt":"2015-06-07T04:00:05","slug":"a-brief-summary-of-the-articles-appearing-in-this-issue-of","status":"publish","type":"post","link":"http:\/\/elkhorndenture.com\/blog\/a-brief-summary-of-the-articles-appearing-in-this-issue-of\/","title":{"rendered":"A brief summary of the articles appearing in this issue of ."},"content":{"rendered":"<p>Recent studies have highlighted the importance of N-methyl-D-aspartate receptor signaling in the neurobiology of major depressive disorder (MDD). In this blinded, placebo-controlled, crossover trial, Nagele et al. (pages 10\u201318) report that inhaled nitrous oxide, a general anesthetic commonly used in dentistry, improved depressive symptoms 24 hours after treatment in patients with treatment-resistant depression. These proof-of-concept data suggest that, like ketamine, this N-methyl-D-aspartate receptor antagonist may have rapid and marked antidepressant effects. (Source: Biological Psychiatry)<br \/>\n<a rel=\"nofollow\" href=\"http:\/\/www.medworm.com\/index.php?rid=113780403&#038;cid=d_11_172_f&#038;fid=34401&#038;url=http%3A%2F%2Fwww.biologicalpsychiatryjournal.com%2Farticle%2FS0006-3223%2815%2900428-X%2Fabstract%3Frss%3Dyes\">MedWorm: Dentistry<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Recent studies have highlighted the importance of N-methyl-D-aspartate receptor signaling in the neurobiology of major depressive disorder (MDD). In this blinded, placebo-controlled, crossover trial, Nagele et al. (pages 10\u201318) report that inhaled nitrous oxide, a general anesthetic commonly used in dentistry, improved depressive symptoms 24 hours after treatment in patients with treatment-resistant depression. These proof-of-concept [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[5],"tags":[8070,6368,3014,734,735,162],"class_list":["post-5662","post","type-post","status-publish","format-standard","hentry","category-dental-news","tag-appearing","tag-articles","tag-brief","tag-issue","tag-summary","tag-this"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p1YapV-1tk","_links":{"self":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts\/5662","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/comments?post=5662"}],"version-history":[{"count":0,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts\/5662\/revisions"}],"wp:attachment":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/media?parent=5662"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/categories?post=5662"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/tags?post=5662"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}