{"id":544,"date":"2012-04-17T05:00:03","date_gmt":"2012-04-17T05:00:03","guid":{"rendered":"http:\/\/elkhorndenture.com\/blog\/dentistry-and-molecular-biology-a-promising-field-for-tooth-agenesis-management\/"},"modified":"2012-04-17T05:00:03","modified_gmt":"2012-04-17T05:00:03","slug":"dentistry-and-molecular-biology-a-promising-field-for-tooth-agenesis-management","status":"publish","type":"post","link":"http:\/\/elkhorndenture.com\/blog\/dentistry-and-molecular-biology-a-promising-field-for-tooth-agenesis-management\/","title":{"rendered":"Dentistry and molecular biology: a promising field for tooth agenesis management."},"content":{"rendered":"<p>Authors: Ramos Boeira Junior B, Echeverrigaray S<br \/>\n    Abstract<br \/>\n    Tooth agenesis is the failure of tooth bud development, causing definitive absence of the tooth. It is the most common dental anomaly, affecting up to one-quarter of the general population. The main cause is related to abnormal function of specific genes which play key roles during odontogenesis, particularly MSX1 and PAX9. MSX1 is a transcription factor highly expressed in the mesenchyme of developing tooth germs, whereas PAX9 is a transcription factor that shows a direct relationship with craniofacial development, particularly the formation of the palate and teeth. Despite the high frequency of tooth agenesis, there are as yet only a restricted number of mutations in MSX1 and PAX9 that have been associated with non-syndrom&#8230;<\/p>\n<div id=\"medworm\">\n<p><b><i>MedWorm Sponsor Message:<\/i><\/b> The blue sky scrub collection offers something for every medical professional. Offering some of the finest <a href=\"http:\/\/www.blueskyscrubs.com\/\">scrub clothing<\/a> in the world.<\/p>\n<\/div>\n<p><a rel=\"nofollow\" href=\"http:\/\/www.medworm.com\/index.php?rid=5931821&#038;cid=d_11_39_f&#038;fid=36115&#038;url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22452934%26dopt%3DAbstract\">MedWorm: Dentistry<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Authors: Ramos Boeira Junior B, Echeverrigaray S Abstract Tooth agenesis is the failure of tooth bud development, causing definitive absence of the tooth. It is the most common dental anomaly, affecting up to one-quarter of the general population. The main cause is related to abnormal function of specific genes which play key roles during odontogenesis, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[5],"tags":[1812,1809,58,1811,560,1808,1810,49],"class_list":["post-544","post","type-post","status-publish","format-standard","hentry","category-dental-news","tag-agenesis","tag-biology","tag-dentistry","tag-field","tag-management","tag-molecular","tag-promising","tag-tooth"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p1YapV-8M","_links":{"self":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts\/544","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/comments?post=544"}],"version-history":[{"count":0,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts\/544\/revisions"}],"wp:attachment":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/media?parent=544"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/categories?post=544"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/tags?post=544"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}