{"id":4825,"date":"2014-10-29T04:00:06","date_gmt":"2014-10-29T04:00:06","guid":{"rendered":"http:\/\/elkhorndenture.com\/blog\/prognostic-significance-of-neural-stem-cell-markers-nestin-and-musashi-1-in-oral-squamous-cell-carcinoma-expression-pattern-of-nestin-in-the-precancerous-stages-of-oral-squamous-epithelium\/"},"modified":"2014-10-29T04:00:06","modified_gmt":"2014-10-29T04:00:06","slug":"prognostic-significance-of-neural-stem-cell-markers-nestin-and-musashi-1-in-oral-squamous-cell-carcinoma-expression-pattern-of-nestin-in-the-precancerous-stages-of-oral-squamous-epithelium","status":"publish","type":"post","link":"http:\/\/elkhorndenture.com\/blog\/prognostic-significance-of-neural-stem-cell-markers-nestin-and-musashi-1-in-oral-squamous-cell-carcinoma-expression-pattern-of-nestin-in-the-precancerous-stages-of-oral-squamous-epithelium\/","title":{"rendered":"Prognostic significance of neural stem cell markers, Nestin and Musashi-1, in oral squamous cell carcinoma: expression pattern of Nestin in the precancerous stages of oral squamous epithelium"},"content":{"rendered":"<p>Conclusions           Expression of Nestin in the preneoplastic lesions indicates its role in the transformation of oral squamous epithelium. Clinicopathological and survival analyses suggest that Nestin and Musashi-1 might be associated with invasion, differentiation and poorer survival in oral squamous cell carcinoma. In addition to their role as independent prognostic indicators, Nestin and Musashi-1 double positivity can be used to select high-risk cases for effective therapy and this is the novel finding of this study.                               Clinical relevance           Nestin and Musashi-1 are found to be independent prognostic markers of oral cancer, and they might be used as molecular targets for effective therapy. (Source: Clinical Oral Investigations)<\/p>\n<div id=\"medworm\">\n<p><b><i>MedWorm Sponsor Message:<\/i><\/b> MedWorm Search is coming back soon. <a href=\"http:\/\/www.MedWorm.com\/\" target=\"_blank\">Watch this space&#8230;<\/a><\/p>\n<\/div>\n<p><a rel=\"nofollow\" href=\"http:\/\/www.medworm.com\/index.php?rid=61417416&#038;cid=d_11_11_f&#038;fid=33454&#038;url=http%3A%2F%2Flink.springer.com%2F10.1007%2Fs00784-014-1341-z\">MedWorm: Dentistry<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Conclusions Expression of Nestin in the preneoplastic lesions indicates its role in the transformation of oral squamous epithelium. Clinicopathological and survival analyses suggest that Nestin and Musashi-1 might be associated with invasion, differentiation and poorer survival in oral squamous cell carcinoma. In addition to their role as independent prognostic indicators, Nestin and Musashi-1 double positivity [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[5],"tags":[3824,525,7254,3267,4713,7251,7250,7249,7,6595,7252,2620,6482,3823,7253,1204],"class_list":["post-4825","post","type-post","status-publish","format-standard","hentry","category-dental-news","tag-carcinoma","tag-cell","tag-epithelium","tag-expression","tag-markers","tag-musashi1","tag-nestin","tag-neural","tag-oral","tag-pattern","tag-precancerous","tag-prognostic","tag-significance","tag-squamous","tag-stages","tag-stem"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p1YapV-1fP","_links":{"self":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts\/4825","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/comments?post=4825"}],"version-history":[{"count":0,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts\/4825\/revisions"}],"wp:attachment":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/media?parent=4825"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/categories?post=4825"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/tags?post=4825"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}