{"id":3037,"date":"2013-09-26T05:00:03","date_gmt":"2013-09-26T05:00:03","guid":{"rendered":"http:\/\/elkhorndenture.com\/blog\/appliance%e2%80%90induced-osteopenia-of-dentoalveolar-bone-in-the-rat-effect-of-reduced-bone-strains-on-serum-bone-markers-and-the-multifunctional-hormone-leptin\/"},"modified":"2013-09-26T05:00:03","modified_gmt":"2013-09-26T05:00:03","slug":"appliance%e2%80%90induced-osteopenia-of-dentoalveolar-bone-in-the-rat-effect-of-reduced-bone-strains-on-serum-bone-markers-and-the-multifunctional-hormone-leptin","status":"publish","type":"post","link":"http:\/\/elkhorndenture.com\/blog\/appliance%e2%80%90induced-osteopenia-of-dentoalveolar-bone-in-the-rat-effect-of-reduced-bone-strains-on-serum-bone-markers-and-the-multifunctional-hormone-leptin\/","title":{"rendered":"Appliance?induced osteopenia of dentoalveolar bone in the rat: effect of reduced bone strains on serum bone markers and the multifunctional hormone leptin"},"content":{"rendered":"<p>To understand, in greater detail, the molecular mechanisms regulating the complex relationship between mechanical strain and alveolar bone metabolism during orthodontic treatment, passive cross?arch palatal springs were bonded to the maxillary molars of 6?wk?old rats, which were killed after 4 and 8\u00a0d. Outcome measures included serum assays for markers of bone formation and resorption and for the multifunctional hormone leptin, and histomorphometry of the inter?radicular bone. The concentration of the bone?formation marker alkaline phosphatase (ALP) was significantly reduced at both time points in the appliance group, accompanied by a 50% reduction in inter?radicular bone volume; however, osteocalcin (bone Gla protein) levels remained unaffected. Bone collagen deoxypyridinolin&#8230;<\/p>\n<div id=\"medworm\">\n<p><b><i>MedWorm Sponsor Message:<\/i><\/b> The blue sky scrub collection offers something for every medical professional. Offering some of the finest <a href=\"http:\/\/www.blueskyscrubs.com\/\">scrub clothing<\/a> in the world.<\/p>\n<\/div>\n<p><a rel=\"nofollow\" href=\"http:\/\/www.medworm.com\/index.php?rid=7623746&#038;cid=d_11_11_f&#038;fid=28259&#038;url=http%3A%2F%2Fonlinelibrary.wiley.com%2Fresolve%2Fdoi%3FDOI%3D10.1111%252Feos.12091\">MedWorm: Dentistry<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>To understand, in greater detail, the molecular mechanisms regulating the complex relationship between mechanical strain and alveolar bone metabolism during orthodontic treatment, passive cross?arch palatal springs were bonded to the maxillary molars of 6?wk?old rats, which were killed after 4 and 8\u00a0d. Outcome measures included serum assays for markers of bone formation and resorption and [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[5],"tags":[5411,70,5413,222,5148,5415,4713,5414,5412,895,4728,1889],"class_list":["post-3037","post","type-post","status-publish","format-standard","hentry","category-dental-news","tag-applianceinduced","tag-bone","tag-dentoalveolar","tag-effect","tag-hormone","tag-leptin","tag-markers","tag-multifunctional","tag-osteopenia","tag-reduced","tag-serum","tag-strains"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p1YapV-MZ","_links":{"self":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts\/3037","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/comments?post=3037"}],"version-history":[{"count":0,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/posts\/3037\/revisions"}],"wp:attachment":[{"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/media?parent=3037"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/categories?post=3037"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/elkhorndenture.com\/blog\/wp-json\/wp\/v2\/tags?post=3037"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}