The effects of static pressure on chondrogenic and osteogenic differentiation in condylar chondrocytes from temporomandibular joint

Temporomandibular disorder (TMD) is a common disease in the oral and maxillofacial region. Orofacial pain, joint sounds, and abnormal mandibular movement are common clinical manifestations of TMD.1,2 The aetiology and pathological mechanisms of TMD are still unclear. Usually, the condyle bears the pressure from jaw movements, and the disc plays an important role in buffering and dispersing pressure. When the disc loses its normal function, the physical microenvironment of the temporomandibular joint (TMJ) will be destroyed and the intra-articular pressure will abnormally elevate. (Source: Archives of Oral Biology)
MedWorm: Dentistry