Should I eXtract Every Six dental trial (SIXES): study protocol for a randomized controlled trial

DiscussionSIXES dental trial investigates whether compensating extraction of upper first permanent molars should be carried out following loss of lower first permanent molars. Currently dentists and orthodontists face a dilemma in clinical decision-making, relying on the lowest level of evidence – expert opinion. SIXES will provide evidence to support decision-making and inform practices and may result in reduced tooth extractions.Trial registration: Clinical Trials.gov Identifier: NCT01591265 (Source: Trials)
MedWorm: Dentistry