Abstract: Matrix metalloproteinases (MMPs) are known to play a key role during orthodontic treatment leading to periodontal remodelling and tooth movement. MMPs may be induced by mechanical forces. However, the role played by toll-like receptors (TLRs) in modulating the effects of the mechanical force on periodontal fibroblasts is not known. To investigate the interaction between mechanical force and TLR stimulation, primary cultures of human periodontal fibroblasts were submitted to centrifugation in the presence of LPS and Pam3Cys, which are known TLR-4 and TLR-2 ligands, respectively. The expression of MMP-1, -2, -3, -8, -9, -10 and -13; TIMP (Tissue Inhibitor of Metalloproteinases) -1, -2 and -4; TNF-? (Tumour Necrosis Factor alpha); IL-1? (Interleukin 1 beta); ERK 1/2 (Extracellular…
MedWorm: Dentistry
Affordable Care Act falls short, ADA research says
The Affordable Care Act falls short in lowering dental care costs, increasing access to care and improving health outcomes, according to research briefs published by the ADA Health Policy Resources Center.
Posted in Dental News.
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– May 11, 2013
Rene Descartes
“I think; therefore I am.”
Quote of the Day
Posted in Quote Of The Day.
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– May 11, 2013
Profiling biomarkers in gingival crevicular fluid using multiplex bead immunoassay
Conclusion: IL-1? levels in GCF correlate with the PDs, BOP and the presence of P. gingivalis in subgingival plaque. Multiplex bead assays can be useful in GCF studies. These findings can help in identifying new diagnostic methods in the diagnosis of periodontal disease. (Source: Archives of Oral Biology)
MedWorm Sponsor Message: The blue sky scrub collection offers something for every medical professional. Offering some of the finest scrub clothing in the world.
Posted in Dental News.
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– May 11, 2013
Local dentist gives free dental care
Dental care can often be expensive but this week, community members were able to receive dental care free of charge.
Posted in Dental News.
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– May 11, 2013
Association challenges Pew issue brief
Washington—The Pew Children’s Dental Campaign acknowledged “errata” in a posted issue brief challenged by the Association as using “erroneous calculations to buttress its arguments that New Zealand’s use of dental therapists is responsible for better oral health among New Zealand children than those in the U.S.”
Posted in Dental News.
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– May 10, 2013
Sun Tzu
He will win who knows when to fight and when not to fight. Discuss
Quote of the Day
Posted in Quote Of The Day.
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– May 10, 2013
Evaluation of primary and secondary stability of titanium implants using different surgical techniques
ConclusionAt 3 weeks after implant installation, independent of the used undersized surgical technique, the %BV in the inner zone (0–500 ?m) peri?implant area was improved due to both condensation of the surrounding bone as also the translocation of host bone particles along the implant surface. Surprisingly, no mechanical beneficial effect of the 25% undersized surgical technique could be observed as compared to the 5% or 15% undersized surgical technique to improve primary or secondary implant stability. (Source: Clinical Oral Implants Research)
MedWorm: Dentistry
Posted in Dental News.
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– May 10, 2013
Between east and west: Jerusalem’s No-Man’s Land
In November of ’48, Moshe Dayan and his Jordanian counterpart Abdullah a-Tal marked up a map.
Posted in Dental News.
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– May 10, 2013
New resource on treating obesity available
Tampa, Fla.—The Obesity Action Coalition and the American College of Physicians have a new free resource for health care professionals who treat excess weight and obesity.
Posted in Dental News.
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– May 9, 2013
