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Effects of growth hormone and ultrasound on mandibular growth in rats: MicroCT and toxicity analyses

Abstract: It has been shown by previous studies that mandibular growth can be enhanced by the systemic administration of recombinant growth hormone (rGH) and/or local application of therapeutic low intensity pulsed ultrasound (LIPUS). The purpose of this study was to determine if local injection of rGH and application of LIPUS to the temporomandibular joint (TMJ) would synergistically enhance mandibular growth. In an animal study, the effect of rGH, LIPUS, and combination of rGH and LIPUS on male Sprague–Dawley rats was observed. Mandibular growth was evaluated by measuring total hemimandibular and condylar bone volume and bone surface area as well as condylar bone mineral density (BMD) after 21 days on dissected rats’ mandibles using micro-computed tomography (MicroCT). The expression…

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3D Systems: Medical Success With 3D Printing

Some speculate that it is destined to become the IBM of the industry. Healthcare professionals were among the first to embrace 3D Systems’ additive manufacturing capabilities.

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Dental debt management tool debuts

Washington—Current and incoming dental students will have access to a newly customized online debt management tool through school financial aid offices, the Association of American Medical Colleges and American Dental Education Association announced Aug. 5 as many students were returning to school.

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Ring Lardner

“A good many young writers make the mistake of enclosing a stamped, self-addressed envelope, big enough for the manuscript to come back in. This is too much of a temptation to the editor.”
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Altered phenotype and function of dendritic cells in individuals with chronic periodontitis

Conclusions: Bacterial-unstimulated m-MDDC from CP exhibited a more immature phenotype but a cytokine profile biased towards proinflammatory response; this pattern was maintained/exacerbated after bacterial stimulation. P. intermedia upregulated co-stimulatory molecules and IFN-gamma expression in CP m-MDDC. These events might contribute to periodontitis pathogenesis. (Source: Archives of Oral Biology)
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Calling All Denture Technicians: Show Off Your Skills AND Get a Chance at $1,000

To celebrate the work of highly skilled denture technicians and elevate the status of the specialty, Candulor is sponsoring its second North American “Art of Denture” Competition, inviting U.S. and Canadian technicians to fabricate fully removable upper and lower dentures supported by locators.

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Results from large international clinical trials provide dentists and patients with a new level of confidence in dental implants

Results from two of the largest international clinical studies performed to date with dental implants have just been published and demonstrate excellent clinical performance. Together, the studies have evaluated more than one thousand Straumann Bone Level implants in Europe, the US and Australia…
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Sunshine Act update

Washington—Rep. Nydia Velazquez, D-N.Y., urged the Centers for Medicare & Medicaid Services July 18 to delay ‘transfer of value’ data collection from physicians and teaching hospitals, including dentists, scheduled to begin Aug. 1 under the Affordable Care Act.

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Rita Mae Brown

“Good judgment comes from experience, and often experience comes from bad judgment.”
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Interleukin-10 gene promoter polymorphisms are associated with cyclosporin A-induced gingival overgrowth in renal transplant patients

Abstract: Objective: Interleukin-10 (IL-10) is an anti-inflammatory cytokine whose genetic polymorphisms are associated with the production of IL-10 and the susceptibility to periodontal diseases. The aim of this study was to investigate the possible association of IL-10 single nucleotide polymorphisms (SNPs) and cyclosporin A (CsA)-induced gingival overgrowth (GO) in renal transplant patients in a Chinese population, taking into account subgingival microbiota as additional variables.Material and methods: A total of 202 patients were dichotomized into two groups: 122 with GO and 80 without GO. The IL-10-1082 SNP, -819 SNP and -592 SNP were measured using an allele-specific PCR method. The levels of subgingival bacteria were measured by real-time PCR. Genotype and allele frequencies were an…
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