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From the bench to the market: the long, sinuous and rocky road

(Source: Journal of Applied Oral Science)

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MedWorm: Dentistry

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Predicting caries risk at 30-months of age in medical settings

At the 45th Annual Meeting & Exhibition of the American Association for Dental Research, researcher Margherita Fontana, University of Michigan School of Dentistry, Ann Arbor, USA, presented a study…
Dentistry News From Medical News Today

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T. S. Eliot

“Humankind cannot stand very much reality.”
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Child and adolescent perceptions of oral health: Life course perspectives

At the 45th Annual Meeting & Exhibition of the American Association for Dental Research, researcher Carl Maida, University of California, Los Angeles, USA, presented a study titled “Child and…
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Timing of primary tooth emergence among U.S. racial and ethnic groups

ConclusionsTooth emergence occurs at a younger age for AI children than it does for contemporary White or Black children in the United States. (Source: Journal of Public Health Dentistry)

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NaF Inhibits Matrix-Bound Cathepsin-Mediated Dentin Matrix Degradation

This study aimed to evaluate the efficacy of NaF on the inhibition of dentin-bound MMPs and CCs. Dentin beams were completely demineralized in 10% phosphoric acid. The baseline total MMP activity and dry masses were measured. Beams were assigned to test groups based on similar MMP activity and dry mass (n = 10/group), and incubated in artificial saliva (control) or artificial saliva with NaF containing 6-238 mM fluoride for 1, 7 and 21 days. The dry mass loss and MMP activities were reassessed at each time point. The proteolytic activity was screened by gelatin zymography. ICTP and CTX released to the incubation medium were analyzed as indices of MMP and cathepsin K activity, respectively. The beams were examined under scanning electron microscopy. All NaF doses reduced the dry mass loss a…
MedWorm: Dentistry

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Frequency of Fluoride Dentifrice Use and Caries Lesions Inhibition and Repair

The clinical relevance of the frequency of fluoride dentifrice (FD) use on enamel caries is based on evidence. However, the relative effect of FD on reduction of demineralization or enhancement of remineralization is unknown and the effect of frequency on root dentine caries has not been explored. The aim of this double-blind, crossover, in situ study, which was conducted in 4 phases of 14 days each, was to evaluate the relationship between the frequency of FD use and enamel and root dentine de- and remineralization. Eighteen volunteers wore palatal appliances containing enamel and root dentine slabs, either sound or carious. Biofilm accumulation on the slab surface was allowed, and 20% sucrose solution was dripped 3 or 8 times per day on the carious and sound slabs, respectively. Voluntee…

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MedWorm: Dentistry

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Influences on preschool children’s oral health?related quality of life as reported by English and Spanish?speaking parents and caregivers

ConclusionsThe overall severity of ECOHIS impacts was low among this population?based sample of young, preschool children, and substantially lower among Spanish versus English speakers. Further studies are warranted to identify sources of these differences in – actual or reported – OHRQoL impacts. (Source: Journal of Public Health Dentistry)

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3 Minutes on a Park Bench with Dr. Joshua Lee from Malden Dental Associates

Dr. Joshua Lee from Malden Dental Associates tells the Patch how he takes care of his own teeth and talks about what made him want to pursue a career in dentistry. Dr. Lee: The Malden area has an ethnically diverse population.

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High percentage of patients prescribed opioids following tooth extraction

In a study published online by JAMA, Brian T. Bateman, M.D., M.Sc., of Brigham and Women’s Hospital, Boston, and colleagues examined nationwide patterns of opioid prescribing following surgical…
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