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Decreased expression of E?cadherin by Porphyromonas gingivalis?lipopolysaccharide attenuates epithelial barrier function

ConclusionThese results suggest that the decrease in E?cad caused by P. gingivalis?LPS leads to destruction of the epithelial barrier function in human gingival epithelial cells, and finally accelerates the inflammatory reaction under the barrier. Antioxidants, particularly vitamin E and l?ascorbic acid 2?phosphate magnesium salt, may restore the impaired function by scavenging ROS, which are related to the decrease in E?cad expression by P. gingivalis?LPS. (Source: Journal of Periodontal Research)

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Fruit juices and smoothies have ‘unacceptably high’ sugar content

Fruit juices and smoothies may contain more sugar than you expect. New research reveals that one juice may contain a child’s recommended sugar intake for a whole day.
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Survival of Dental Implants Placed in Grafted and Nongrafted Bone: A Retrospective Study in a University Setting.

CONCLUSION: There was no difference in the dental implant survival rate when implants were placed in native bone or bone-grafted sites. Smoking and lack of professional maintenance were significantly related to increased implant loss. PMID: 27004278 [PubMed – in process] (Source: International Journal of Oral and Maxillofacial Implants)

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5 keys to choosing a senior dental savings plan

While many employers provide employees with insurance that covers dental costs, that coverage often comes to an abrupt end when an employee retires. Medicare doesn’t cover most routine dental services.

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MicroRNA-146a is abundant in extracellular vesicles released by osteoclasts

At the 45th Annual Meeting & Exhibition of the American Association for Dental Research, researcher Lexie Holliday, University of Florida, Gainesville, USA, presented a study titled “MicroRNA-146a…
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Etiology and pathogenesis of dental erosion

Kanzow, Philipp / Wegehaupt, Florian J. / Attin, Thomas / Wiegand, AnnettePage 275 – 278The condition of dental erosion is defined as acid-related loss of tooth structure which does not involve microorganisms. Depending on the origin of the acid, extrinsic (usually caused by acids in food) and intrinsic (caused by endogenous acid) erosion can be distinguished. The presence and severity of erosive defects depend on various parameters such as nutrition, saliva, general diseases, and mechanical stress by abrasion and attrition. As an example, dietary habits which involve frequent intake of acidic food and beverages, occupational acid exposure, as well as certain drugs or diseases that affect saliva flow rate are accompanied by an increased risk of erosive dental hard tissue defects. By a thor…

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Gym members donating to “Get Mary’s Smile Back”

“I jump roped yesterday. I was crying in there because I never jumped rope since I was in my middle school,” said Hetzel.

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Adjunctive minocycline microspheres

At the 45th Annual Meeting & Exhibition of the American Association for Dental Research, researcher Ricardo Teles, University of North Carolina, Chapel Hill, USA and The Forsyth Institute, Boston…
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Severe tooth loss after root damage caused by predrilled intermaxillary fixation screw: a case report

Abstract Intermaxillary fixation (IMF) with screws is routinely used as a conservative therapy or to obtain normal occlusion during the surgical procedure of open reduction and internal fixation for treating mandibular fractures. The risk of iatrogenic dental damage caused by interdental drilling is widely known. Several side effects are described, including loss of response to pulp sensibility testing, root fracture, and, loss of the tooth. This is a case report about a young man who had undergone temporary IMF treatment with a single proven root damage. The patient did not appear for follow?up but he presented 5 years afterward with local purulent osteomyelitis concerning the affected and the adjacent teeth. Osteotomy and extraction of two premolars and one molar were necessary for reh…

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Small molecule replacement therapy to rescue craniofacial defects

At the 45th Annual Meeting & Exhibition of the American Association for Dental Research, researcher Shihai Jia, University of Utah, Salt Lake City, USA, presented a study titled “Small Molecule…
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