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Simvastatin inhibits the expression of inflammatory cytokines and cell adhesion molecules induced by LPS in human dental pulp cells

ConclusionsSimvastatin has a suppressing effect on LPS?induced inflammatory cytokine, cell adhesion molecules, and NF??B transcription factors in HDPCs. Therefore, simvastatin might be a useful candidate as a pulp capping agent in vital pulp therapy.This article is protected by copyright. All rights reserved. (Source: International Endodontic Journal)

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MedWorm: Dentistry

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Dissolution, dislocation and dimensional changes of endodontic sealers after a solubility challenge: A micro?CT approach

ConclusionsAlthough the solubility of both sealers was similar using this novel micro?CT approach, MTA Fillapex was associated with significant dimensional changes related to material extrusion through the apex after PBS storage compared to AH Plus.This article is protected by copyright. All rights reserved. (Source: International Endodontic Journal)
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Frank Zappa

“I think it is good that books still exist, but they do make me sleepy.”
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Modified Activation Technique for Nasal Stent of Nasoalveolar Molding Appliance for Columellar Lengthening in Bilateral Cleft Lip/Palate

This article proposes a modified activation technique of the nasal stent for a NAM appliance for columellar lengthening in bilateral cleft lip/palate patients. The design highlights relining of the columellar portion of the nasal stent and the wire?bending of the nasal stent to achieve desirable results within the limited span of plasticity of the nasal cartilages. With this technique the vertical taping of the premaxilla to the oral plate can be avoided. (Source: Journal of Prosthodontics)
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Ted Morgan

“Howard Hughes was able to afford the luxury of madness, like a man who not only thinks he is Napoleon but hires an army to prove it.”
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American cancer society head and neck cancer survivorship care guideline

Answer questions and earn CME/CNE The American Cancer Society Head and Neck Cancer Survivorship Care Guideline was developed to assist primary care clinicians and other health practitioners with the care of head and neck cancer survivors, including monitoring for recurrence, screening for second primary cancers, assessment and management of long?term and late effects, health promotion, and care coordination. A systematic review of the literature was conducted using PubMed through April 2015, and a multidisciplinary expert workgroup with expertise in primary care, dentistry, surgical oncology, medical oncology, radiation oncology, clinical psychology, speech?language pathology, physical medicine and rehabilitation, the patient perspective, and nursing was assembled. While the guideline …
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Injected mix of bone-augmenting agents causes new bone growth in mouse jaws

The part of the jawbone containing tooth sockets is known as alveolar bone, and its loss over time or following dental disease may ultimately result in tooth loss. While dentures can be used as a tooth replacement, the mechanical stimuli under the dentures causes further bone loss.

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Sydney Smith

“You must not think me necessarily foolish because I am facetious, nor will I consider you necessarily wise because you are grave.”
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Cleansing effect of acidic L-arginine on human oral biofilm

Dental plaque formed on tooth surfaces is a complex ecosystem composed of diverse oral bacteria and salivary components. Accumulation of dental plaque is a risk factor for dental caries and periodontal disease… (Source: BMC Oral Health)
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Henry Fielding

“Now, in reality, the world have paid too great a compliment to critics, and have imagined them to be men of much greater profundity than they really are.”
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