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Jerry Seinfeld

“Where lipstick is concerned, the important thing is not color, but to accept God’s final word on where your lips end.”
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A comparative assessment of enamel mineral content and Streptococcus mutans population between conventional composites and composites containing nano amorphous calcium phosphate in fixed orthodontic patients: a split-mouth randomized clinical trial.

CONCLUSION: NACP-containing composites have the potential to inhibit mineral content loss and S.mutans colonization around orthodontic brackets during fixed orthodontic treatments. TRIAL REGISTRATION: This trial was not registered. PROTOCOL: The protocol was not published before trial commencement. PMID: 26969421 [PubMed – as supplied by publisher] (Source: European Journal of Orthodontics)
MedWorm: Dentistry

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Ambrose Bierce

“Politics, n. Strife of interests masquerading as a contest of principles.”
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Effects of fixed orthodontic treatment using conventional (two-piece) versus metal injection moulding brackets on hair nickel and chromium levels: a double-blind randomized clinical trial.

CONCLUSION: Hair nickel and chromium levels might increase about 185-200% after 6 months. They might not be affected by bracket types. Gender and age might not influence the baseline or 6th-month levels of both metals. Gender might however interact with orthodontic treatment, only in the case of chromium. REGISTRATION: The research is registered offline (thesis) and online (IR.AJUMS.REC.1394.516). PROTOCOL: The protocol was pre-determined before any experiments begin. FUNDING: The study was self-funded by the authors. PMID: 26969422 [PubMed – as supplied by publisher] (Source: European Journal of Orthodontics)

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MedWorm: Dentistry

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Thomas Neill

“Of those who say nothing, few are silent.”
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A survey of general dentists regarding orthodontic retention procedures.

CONCLUSIONS: Swiss general dentists have good knowledge of orthodontic retention and follow-up procedures. Nevertheless, introduction of clinical guidelines including information on the possible side-effects of bonded retention is justified. PMID: 26969423 [PubMed – as supplied by publisher] (Source: European Journal of Orthodontics)
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George Orwell

“In certain kinds of writing, particularly in art criticism and literary criticism, it is normal to come across long passages which are almost completely lacking in meaning.”
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Bleeding after tooth extraction in patients taking aspirin and clopidogrel (Plavix®) compared with healthy controls

The risk of perioperative bleeding is high in patients who take aspirin and clopidogrel after a percutaneous coronary intervention, and whether to stop the drugs is a matter of concern for dentists. The aim of this study was to answer the specific question: should aspirin and clopidogrel bisulphate (Plavix®) be discontinued during a conventional forceps extraction? We studied 64 patients during the first year after percutaneous insertion of coronary stents who were taking aspirin (ASA) 80mg and clopidogrel (Plavix®) 75mg, and 50 healthy patients who were to have a conventional forceps extraction at this polyclinic in 2013-2014and acted as controls. (Source: The British Journal of Oral and Maxillofacial Surgery)
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Logan Pearsall Smith

“The denunciation of the young is a necessary part of the hygiene of older people, and greatly assists in the circulation of their blood.”
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Oral Cancer and Cancer Stem Cells: Relevance to Oral Cancer Risk Factors, Premalignant Lesions, and Treatment

Abstract Cancer stem cells are recognized as the most critical cancer cells. They are responsible for cancer progression, the development of metastasis, and treatment failures. There are a number of well-studied surface proteins and enzymatic processes that can be used to isolate cancer stem cells from the bulk of the other cancer cells. The role of cancer stems cells in premalignant lesions of the oral cancer is poorly understood but slowly evolving. Novel therapies are being developed to more effectively eradicate cancer stem cells and improve patient outcomes. Efforts to improve our understanding of this important subpopulation of cancer cells is vital in directing further studies to advance our ability to prevent patients from developing oral cancer and to providing more effec…
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