Effects of epicatechin, a crosslinking agent, on human dental pulp cells cultured in collagen scaffolds

Conclusions Our results revealed that ECN promoted the proliferation and differentiation of hDPCs. Furthermore, the differentiation was regulated by the ERK signaling pathway. Changes in mechanical properties are related to cell fate, including proliferation and differentiation. Therefore, our study suggests the ECN treatment might be desirable for dentin-pulp complex regeneration. (Source: Journal of Applied Oral Science)
MedWorm: Dentistry